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Persist application data from Node into real databases — connect to PostgreSQL with the node-postgres driver, run safe parameterised queries, and pool connections for performance. Layer an ORM such as Prisma or Sequelize on top, understand migrations, and store documents in MongoDB with Mongoose. You finish able to design and build the data-access layer of a production Node service.
Go beyond "hello world" and learn to structure a production-grade Express API — modular routers, a middleware pipeline you actually understand, request validation, environment config and a single centralised error handler. You will finish able to lay out an Express codebase that other engineers can extend safely.
Learn to secure a Node.js API end to end — hash passwords with bcrypt, issue and verify JWTs, protect routes with auth middleware, manage sessions and cookies safely, and harden the app with helmet, CORS, rate limiting and input validation. You walk away able to take an unprotected Express API and make it genuinely safe against the common OWASP attacks.